Three lucky fishermen have been rescued from shark-infested waters in the Gulf of Mexico.

The men had been stranded in the water after their 24-foot fishing boat sank at around 10am on Saturday morning, leaving them without any means of communication.

US Coast Guard Heartland said that two of the men were fending off sharks with their hands when a rescue helicopter arrived. They were later treated for shark bites and are in a stable condition in hospital.

After more than 24 hours in the water, all three were also at risk of hypothermia.

Dramatic footage from the rescue showed the men in lifejackets in the sea.

One man was hoisted out of the water by a helicopter, while two others were pulled onto a rescue boat, US Coast Guard Station Venice said.

The men were rescued around 25 miles from Empire, a small community southeast of New Orleans.

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One of the boater's life jackets is torn due to a shark attack. Pic: U.S. Coast Guard Heartland/Facebook
Image:
One of the boater’s life jackets was torn due to a shark attack. Pic: U.S. Coast Guard Heartland/Facebook

US Coast Guard Heartland said a concerned family member had reported the men missing on Saturday evening.

This sparked a search spanning 1,250 square miles – slightly larger than the state of Rhode Island.

The two injured men were hoisted onto a helicopter. Pic: US Coast Guard Heartland/Facebook
Image:
The two injured men were hoisted onto a helicopter. Pic: US Coast Guard Heartland/Facebook

In a post about the rescue on Facebook, the guard said they were “rescued just in the nick of time”.

Investigators have not said what caused the fishing boat to sink, The Sun Herald reported officials as saying.

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